Artroben, 11.6 Oz

A Medical Food for the dietary management of osteoarthritis and musculoskeletal inflammation related to athletic or other physical activity

• FDA category in between dietary supplements and drugs
• Requires a higher level of science than dietary supplements
• Adequate to justify the claim that they are beneficial for management of a disease or condition
• Ingredients must be Generally recognized as safe (GRAS)

Why is Arthroben™ better? 

Because it effectively manages inflammation and improves physical performance and mobility in osteoarthritis sufferers and yet is exceptionally safe.

1. As effective as Naproxen in managing knee osteoarthritis¹
   1. The flavocoxid ingredient in Arthroben was shown to be as effective as Naproxen in managing knee 
osteoarthritis¹
2. Extensively researched collagen peptide ingredients stimulate cartilage and connective tissue repair
   1. Demonstrated ability to increase collagen AND proteoglycan synthesis
   2. Exerts effect on total cartilage mass
3. Exceptionally safe
   1. Gentle on the GI tract²
   2. Balanced inhibition of COX-1, COX-2, and 5-LOX pathways 
   3. Selective or unbalanced inhibition of an individual COX or LOX pathway is believed to result in most of the common side effects associated with chronic NSAID use.
   4. Little or no effect on Pro-times in patients taking warfarin

Most arthritis sufferers use prescription or over-the-counter NSAIDs 
and often suffer serious side effects. As a medical food, Arthroben provides dietary management of osteoarthritis that is both safe and effective.

ARTHROBEN's 4 pronged approach to the dietary management of osteoarthritis:

1. Reduces inflammation—balanced COX and LOX inhibition, virtually free of negative side effects
2. Potent antioxidant protection to reduce joint degeneration
3. Stimulates cartilage and connective tissue repair
4. Improves physical performance and mobility

KEY ACTIVES IN ARTHROBEN™:

Flavocoxid


Flavocoxid is a proprietary blend of the flavonoids baica­lin and catechin that was shown as effective as naproxen in managing knee osteoarthritis, and produced improve­ments in 87% of patients.¹


Dual Action of Flavocoxid:

1. Balanced inhibition of COX-1, COX-2 and 5-LOX pathways. This balanced down-regulation, though weaker than traditional NSAIDs and selective COX-2 inhibitor drugs, is not associated with the side effects commonly seen with selective COX inhibitors.

2. By acting as a strong antioxidant to limit free radicals and oxidative damage to cartilage and other connective tissue of the joints.

Fortigel® & Verisol® 
Fortigel® & Verisol® are standardized mixtures of collagen peptides derived from a patented process of hydrolysis of bovine type I collagen. These ingredients boost anabolic processes in cartilage and connective tissues and provide building blocks for all collagen in the body.

Fortigel

16 human clinical trials (approximately 2800) subjects demonstrating a positive effect on joint health 

• Reduced need of analgesics
• Increased joint mobility
• Improved physical performance 
• Improved radiographic markers of cartilage health

Verisol® 
Verisol® (like Fortigel®) stimulates anabolic processes in connective tissue 

• Tested in two recent human clinical studies (pre-publication) for its effects on type I collagen in skin
• Improved skin elasticity and collagen type I content

Dr. David Brady

Chief Medical Officer, Designs for Health